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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea1de4053e8f2bfff1115f2976187eabe15f0f4244acc534bd02dc47e831de4' 
  AND token = '0BJBEePSbW+wJnuZXu40B7czY9jrRM44ZeQId7RndzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}