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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d4210d1079a1921e8a7fe1b7884032b5caf3200334643a903811f7fb0c7e29' 
  AND token = 'GkolOh/QSDBIZ47Io9F/EYadsVbD2B+bsMnIzFGQc6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}