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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b581e79ad8c20531b1d5cba11100983f221174d89918d3e6bb71141d0e564149' 
  AND token = 'xHjl0mZ3OUmH/lnEmsi8x1wTnDZZ1zL98wvEivLkvnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}