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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435ec3d9d62f947afd47319addf53eb02b744b5dba0b49edd9f562b4018d5830' 
  AND token = 'je7LUANmDGNsvHyF3DCePaxiLi1UzD88nA0nHS+Z4yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}