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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c31f45c59ee8a0039ede5b7334220d1889cbeaf0fc3a4e08317b146e15c93fb' 
  AND token = 'j8SHUWzLfWoqRG8kAipvaDoQBwr4VVc+NPuAtcJBkIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}