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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3f7aeaae6f47af2551c346d9efcaecb3a9ac65ac1b326e9ab269ca8c99eb79' 
  AND token = 'QFSjjzz8bdtoKLzWc3Pn3wmE+XFLVowUL6FC2rmV26M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}