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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272e724b09efeeb15aa3de9b8c2fc2dd7649ba9a78324649875d38e50a9a2417' 
  AND token = 'mVdYJc7IuFEO+NEK2+Z7fMxF4oGzHT9Qd3z1Y2ZIsIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}