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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f9d93d1af24edc9ceb593d5c8f1209bdeb3e649c2d2f2013cbe1ab15b70a2a4' 
  AND token = 'GHnS9sM1atSmpzP6dS8UAb2C/woXe+xtQrp0cZCGI0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}