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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e21b37650d319e71d8ef9a71c11cc5c9078e085ebed6f2edc5751aead2f985' 
  AND token = '4YeExbY1v6O6BP4eOhxGaEzERoDAvrHaCNe8qu1mUmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}