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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48a28cfccb270bc8c236ededbaa59e33f09d6e4c8d6a41d33da63365996c43cb' 
  AND token = 'pQz/PHV8NkrTL8b3p3euY2yb8Ur4jBVD/TfhR/7M0wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}