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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeee32c4be949a804ab3d03566362e694a52421cb3d7d82ad729b3c5d643ed28' 
  AND token = 'O2KV76MKzq+OAuUYQtY1xfSLVUDQdARCtOUsP2dYZ/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}