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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ad50b1c92dcb49f5f42e76a71ac5f076cb04a8cde3475f4587dcb4d40aaef7' 
  AND token = '1URxGe+mtqQopM/8rOM8BN9j3TtWVcIqdGV/zdiujJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}