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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa45040b213a104a010b6b372c3a50505973ed42f7e160ca554aaf803e84da03' 
  AND token = 'ZUZrDr2kaZl6GO0+JeiIjw2ogu9D9Wd9TU0Yh9TPUcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}