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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5669d2e182f51e9e561b66a8670c31b0f0c8a397227bdfa45a3eb52fced0bc' 
  AND token = '/s/RbTmE7LOXPAtRWdV43pb4bYEK3dj5WLAyo8zSsNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}