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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f42241739c6020a3778e51931aeb3ab40be60a0cee13b6b15ba71151617d953' 
  AND token = '6RPLvgQRnceMsg9aAsGHqWONXAE/8ZA2qKp20EesGv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}