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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489f2205ab58c4a9d6ed29c7592cb5a47bb4c9574c23bf7759d00bdaef6bc592' 
  AND token = 'smLMZeKc0iZqLqWyG30RPcY+qevyqRUBgd0kBNml0LI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}