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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291894a85d493ecd345376291a9719d8799742ab592ff5d3a030221f0f04aedb' 
  AND token = 'aSOiOeb3PEZ43hBm8j+0FhWgldDvARtmUi51oUx1Bdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}