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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2103be821321d2a136ae89b71c7527c0e88d1c8bca347be6d298aad5c524e22a' 
  AND token = '+LNP1iuBCyQbTY4fS4dIBRQaIwMPkeSvHxp2/65Wa/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}