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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b628914dbfb9f36baa278f633f33655d3eaa93e06709071a0b455051dee91981' 
  AND token = 'Xzp26bvgN8zbQ8SS59DsKIrM+hUh7li6ZNRZGdvYhfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}