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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10681ed7ffa866b411c8160f49a4e6ea0750f4490230d9d76419d9498a24fd90' 
  AND token = 'g0aFQQkaQImcbuC/IRdD6czj0kEFapG6tOelkUlBZqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}