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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280cb2f9031936f244f30c9bc00c7612739c89d1f69b275d35665eb1ec030f9e' 
  AND token = 'VamUc3gS71Nt4+PryGgc8KF1yvVjD2vpAvHNydbaQGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}