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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74498f687d7845b7203ce8b855f8dd57b05d76ae3bbeb06be4b1a090b8820180' 
  AND token = '2q/2jPAe3Jxm8y4IoYVVFazzUul9thVWjfhCfo0MYXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}