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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010060cb8da9c376f4aa47d3748a05b6a53e0b2cb7915fa7a11305e2cf15b047' 
  AND token = 'U2e5z4YmHtcCwfTLoVOTHt9xqylvWRx0HrZhj+TkTw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}