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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125d4bdf1cbb21a2186a33a5d9ff2c109df2110422cd267d0da2b61feed7b888' 
  AND token = 'KDjMHwbAOyCk4kyaHyNA+OUXqQYq0JIyN2t4nDkENRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}