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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfcc7cd0315cf3bb1cd209c778d80a052a9922503cbe202c7d10f49342d3a8eb' 
  AND token = 'sjTcZYF56a8KL8mBIeF9B5zFMkkivxP/vuU+9cQ2M40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}