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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94b0cb2cb852f57f59152565cb646bcc2d75a07d42393f38db3148b10b15da5c' 
  AND token = 'l0nQovOuN5yAkelftTVW29wHmuzNhyNT/fH/r9x3GpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}