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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '099721d865b6b6659d3884ead126ad0e2cd347ed83f9b7dbb2798fc2d57644ce' 
  AND token = 'ook4ZCcLs4SWgsI3+32zDTuy4rxIuPr9gj5XVvIfoK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}