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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c66926478838ade8f870e2de2082684a8ce049e4b68424b7f7a3b5d966a4d41' 
  AND token = 'IgIX5lwb/p6jnBolOg2GTiIJWTB3d/zXS05CpyndLjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}