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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e15ec6c07411e4c337a9c33bb2965528c93f1a3f15ae40011ca2a75adca9d0' 
  AND token = 'RK0VBKrQfXNZbLRQN81nIWRO/S4A+vigaFwZCINepbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}