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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6c23972cfefd0351823d893352bd0688284d3b0a915f48c6acb1c1f2b7f114' 
  AND token = 'bxMS2kqvgD/ODV2I1bwETb3ZgS1qmW3AvVIsygpNZzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}