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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '959c860e4b706f165c4b14b085ed05082ad6fa5a284e23ea32f2d8e7e9afdb4f' 
  AND token = 'aW3oxCQAdvKTxa03HQrcE+bR0DzPpWfpOdiOE9KvzG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}