SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440e21473cfa21d7c1ebf1dbef80abbde2dc8e7301bc6c47881d49e98f39ae4c' 
  AND token = 'UOn/wIw2t+koRRK3n3Q5uzwZ66Bk7uEcOiyBCo5IuXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}