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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f438ea7d3e51de171ca365528acf054f7b5101dbfdbd7d8e870f63de2ea22f0' 
  AND token = 'eWDpRKuNI1ZpwHbDQx42xHB2uCBNzlxmVxJ74Qe5Z40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}