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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f392bae82fc141d8e3d5cf15f2b81f1d164848f040c080c657b06fd4020b968' 
  AND token = 'l+KXU7PABtiK0tpW0KOBgQaG8RnDAyBj4b5iy+/m7gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}